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. Author manuscript; available in PMC: 2019 Sep 18.
Published in final edited form as: Circulation. 2018 Sep 18;138(12):1224–1235. doi: 10.1161/CIRCULATIONAHA.118.035420

Figure 6. Ltbp2 is upregulated in CFbs of all strains after injury.

Figure 6

(A) Venn diagram depicting the number of overlapping upregulated genes across all three strains after ISO treatment. (B) Average FPKM values for Ltbp2 in all three strains after 21 days of ISO treatment. (C) RT-qPCR analysis of Ltbp2 after ISO treatment (n=7–9/strain/condition). (D) IHC of heart sections stained for LTBP2 (red) and DDR2 (green) or αSMA (green) after ISO treatment and TAC injury. DAPI was used to stain nuclei. FPKM: fragments per kilobase of transcript per million mapped reads. TAC: transverse aortic constriction. Data presented as mean ± SEM. Student t-test, *P < 0.05. Scale bar: 50μm