Table 2.
Univariate and multivariate analyses of prognosis factors for survival in PDAC patients. HR: Hazard ratio; CI: confidence interval. The bold number represents the p-values with significant difference.
Prognostic parameter | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95%CI | P value | HR | 95% CI | P value | |
WNT7A (high vs. low) | 2.258 | 1.333–3.824 | 0.002 | 1.973 | 1.127–3.453 | 0.017 |
Age (≥60 vs.<60) | 1.238 | 0.781–1.962 | 0.364 | |||
Gender (male vs. female) | 1.099 | 0.863–1.400 | 0.445 | |||
Tumor location (head vs. body/tail) | 0.946 | 0.750–1.194 | 0.641 | |||
Size (>3 cm vs. ≤3 cm) | 1.387 | 0.759–2.535 | 0.288 | |||
Tumor differentiation (moderate/poor vs. well) | 1.865 | 1.151–3.021 | 0.011 | 2.649 | 1.542–4.551 | 0.000 |
T classification (T3/T4 vs. T1/T2) | 1.018 | 0.760–1.364 | 0.905 | |||
N classification (present vs. absent) | 2.119 | 1.305–3.440 | 0.002 | 2.322 | 1.359–3.967 | 0.002 |
M classification (present vs. absent) | 1.757 | 0.429–7.189 | 0.443 | |||
AJCC stage (III/IV vs. I/II) | 1.757 | 0.429–7.189 | 0.433 | |||
Neural invasion (present vs. absent) | 0.909 | 0.719–1.150 | 0.427 |