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. 2018 Oct 25;8:15791. doi: 10.1038/s41598-018-34000-x

Figure 8.

Figure 8

Schematic drawing of uracil repair pathway in M. acetivorans. Left pathway: Uracil in DNA is recognized by UDG to initiate the BER pathway. The resultant AP site is cleaved by either ExoIII or EndoQ. EndoIV in M. acetivorans may also act on AP site, although it is not drawn in this scheme. Right pathway: The other pathways of uracil repair are initiated by a direct DNA backbone cleavage by ExoIII or EndoQ (Alternative excision repair (AER) pathway). The resultant nicked DNA is subjected to the downstream repair pathway.