Table 4.
Confirmation of the association of selected genes with COPD/or lung function by literature reviewing in PubMed databank with ((“COPD” OR “Lung Function”) AND “name of each selected gene”).
| Gene Symbol | Probe ID | Number of studies | References (PMIDs) | |
|---|---|---|---|---|
| 1. | PPP4R4 | 233002_at | 1 | 28170284 |
| 2. | THSD4 | 222835_at | 6 | 27564456, 24286382, 23932459, 22461431, 21965014, 20010834 |
| 3. | NRG1 | 206343_s_at | 15 | 28950338, 28901268, 28604730, 28396363, 28391773, 27626312, 26837769, 26200269, 25870798, 25531467, 25501131, 25384085, 24469108, 23390248, 22665269 |
| 4. | SCGB1A1 | 205725_at | 4 | 27081700, 26937342, 26159408, 23144326 |
| 5. | AHRR | 229354_at | 9 | 28854564, 29262847, 28100713, 28056099, 27924164, 27632354, 26667048, 22232023, 18172554 |
| 6. | CYP1A1 | 205749_at | 108 | 29212267, 29076184, 28827732, 28283091, and etc. |
| 7. | CYP1B1 | 202437_s_at | 38 | 29110844, 28858732, and etc. |
| 8. | PRDM11 | 229687_s_at | 1 | 28938616 |
| 9. | CBR3 | 205379_at | 1 | 26916823 |
| 10. | AKR1C1 | 217626_at | 8 | 29344298, 28210161, 26338969, 24976539, 23534707, 23474755, 17266043, 16915569 |
| 11. | AKR1C3 | 209160_at | 7 | 23534707, 28704416, 27629782, 25603868, 23665002, 23519145, 15284179 |
| 12. | HTR2B | 206638_at | 1 | 27301951 |
| 13. | GRM1 | 207299_s_at | 1 | 23303475 |
| 14. | CYP4Z1 | 237395_at | 1 | 19473719 |
| 15. | UCHL1 | 201387_s_at | 5 | 28688920, 25615526, 23534707, 21143527, 17108109 |
| 16. | CABYR | 219928_s_at | 5 | 26938915, 26843620, 24362251, 17317841, 21274509 |
| 17. | GPRC5A | 203108_at | 10 | 29382653, 28849235, 28088789, 26447616, 25621293, 25311788, 23154545, 22239913, 20686609, 20563252 |
| 18. | CCDC37 | 243758_at | 2 | 26200272, 22011669 |
| 19. | GLI3 | 227376_at | 3 | 27146893, 23736020, 23667589 |
| 20. | ABCC3 | 208161_s_at | 4 | 24176985, 23369236, 22699933, 19107936 |
| 21. | SAMD5 | 228653_at | 1 | 25411851 |
| 22. | RASSF10 | 238755_at | 1 | 24433832 |
| 23. | USP27X | 230620_at | 1 | 27013495 |
| 24. | NR0B1 | 206645_s_at | 1 | 28965760 |
| 25. | PLAG1 | 205372_at | 2 | 29305497, 29249655 |
| 26. | SCGB3A1 | 230378_at | 5 | 26937342, 21636547, 20849603, 20660313, 19334046 |
| 27. | LHX6 | 219884_at | 4 | 28900494, 28396596, 27610375, 24157876 |
| 28. | LINC00942 | 1558308_at | 0 | — |
| 29. | REEP1 | 204364_s_at | 0 | — |
| 30. | C6orf164 | 230506_at | 0 | — |
| 31. | LINC00589 | 232718_at | 0 | — |
| 32. | JAKMIP3 | 233076_at | 0 | — |
| 33. | LINC00930 | 1556768_at | 0 | — |
| 34. | DNHD1 | 229631_at | 0 | — |
| 35. | TMCC3 | 235146_at | 0 | — |
| 36. | ADH7 | 210505_at | 0 | — |
| 37. | PRKAR2B | 203680_at | 0 | — |
| 38. | GAD1 | 205278_at | 0 | — |
| 39. | LOC338667 | 1564786_at | 0 | — |
| 40. | CYB5A | 217021_at | 0 | — |
| 41. | PIEZO2 | 219602_s_at | 0 | — |
| 42. | SLITRK6 | 235976_at | 0 | — |
| 43. | KCNA1 | 230849_at | 0 | — |
| 44. | LOC100507560 | 231379_at | 0 | — |