Figure 2.

The visual predictive checks (VPCs) for the hypothetical one‐compartment population pharmacokinetic model. The left and right columns of the figure display VPCs via regression and empirical bin selection, respectively. For all plots, the blue solid line represents the observed median and the blue dashed lines represent the observed 10th and 90th percentiles. Similarly, for all plots, the red solid line represents the simulated median and the red dashed lines represent the simulated 10th and 90th percentiles. AQR, additive quantile regression.