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Mavrilimumab one‐compartment Michaelis‐Menten model (MM; solid line) and target‐mediated drug disposition (TMDD; dashed line) model, in which the base parameter values are in Table 1 and each plot shows a sensitivity analysis where the parameters in the title is changed from 0.1‐fold to 10‐fold. The dot shows critical concentration. For the TMDD model, k syn = V max/V c, Kss = KM
