Table I.
Median expression and number of cases classified as high for each marker.
| Marker | Median | LG, n (%) | LGwHG, n (%) | HG, n (%) | AdCa, n (%) |
|---|---|---|---|---|---|
| Lgr5 | 9.84% | 10 (50.0) | 10 (55.6) | 8 (42.1) | 12 (54.5) |
| SOX2 | 50.5 cells/mm2 | 8 (40.0) | 10 (55.6) | 9 (47.4) | 12 (54.5) |
| CD8 | 293.5 cells/mm2 | 5 (25.0) | 9 (50.0) | 12 (63.2) | 13 (59.1) |
| Foxp3 | 194.8 cells/mm2 | 2 (10.0) | 7 (38.9) | 13 (68.4) | 18 (81.8) |
| PDL1 | 8.01% | 2 (10.0) | 8 (44.4) | 14 (73.7) | 16 (72.7) |
LG, low grade adenoma; LGwHG, low grade adenoma with high grade areas; HG, high grade adenoma; AdCa, adenocarcinoma; Lgr5, Leucine-rich repeat-containing G-protein coupled receptor-5; SOX2, sex determining region Y-box 2; CD8, cluster of differentiation 8; Foxp3, forkhead box P3; PD-L1, programmed death-ligand 1.