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. 2018 Sep 18;16(5):6293–6298. doi: 10.3892/ol.2018.9454

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Copyright: © Lv et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Upregulation of miR-661 activates the Wnt signaling pathway in vitro. (A) Relative expression of cyclin D1, TCF4 and β-catenin was detected using western blotting following cell transfection with miR-NC or miR-661 mimic in PANC-1 cells at 48 h. (B) Relative expression of cyclin D1, TCF4 and β-catenin was detected using western blotting following cell transfection with miR-NC or miR-661 inhibitor in ASPC-1 cells at 48 h. Data are reported as the mean ± standard deviation of 3 independent experiments. miRNA/miR, microRNA; TCF4, transcription factor; NC, negative control.