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. 2018 Sep 11;16(5):6566–6572. doi: 10.3892/ol.2018.9427

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Confirmation of BCL-2 as the target gene of mir-34a in SN-SCC. (A) Display of the binding site of BCL-2 and miR-34a. (B) The luciferase activities in RPMI-2650 cells transfected with BCL-2-3′-UTR-wild (WT) or BCL-2-3′-UTR- mutant (Mut). (C) Relative BCL-2 mRNA and protein expression using RT-PCR and western blot analysis in RPMI-2650 cells. **P<0.01; ***P<0.001; ^###P<0.001. BCL-2, B-cell lymphoma-2; SN-SCC, sinonasal squamous cell carcinoma.