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. 2018 Sep 18;16(5):6472–6478. doi: 10.3892/ol.2018.9451

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Expression of miR-491-5p is significantly downregulated in OS tissues and cells. (A) Expression of miR-491-5p was downregulated in OS tissues compared with adjacent normal tissues (n=36) by RT-qPCR analysis. U6 was used as the internal control. (B) Expression of miR-491-5p was downregulated in 4 different OS cell lines (KHOS, LM7, U2OS, and MG-63) compared with a normal osteoblast cell line (Nhost). U6 was used as the internal control. *P<0.05, **P<0.01 compared with Nhost. miR, microRNA' OS, osteosarcoma.