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. 2018 Sep 20;16(5):6275–6282. doi: 10.3892/ol.2018.9470

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Copyright: © Jin et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — The tumor growth inhibition and survival rate of BALB/c nude mice transplanted with A549 cells. (A) The tumor growth inhibition effect in transplanted nude mice. The tumor volume of the ATV and cisplatin group was significantly lower than that of the PBS group (P<0.01). (B) The survival rate of xenograft tumor nude mice. (C) The survival rate of orthotopic tumor nude mice models. (D) The xenografted tumors were removed and measured at the 30th day and the lungs from orthotopic tumor nude mice models were removed on the 28th day. All values represent the mean ± SD. **P<0.01 vs. PBS group. PBS, phosphate-buffered saline; MOI, multiplicity of infection; SD, standard deviation; Ad5, human adenovirus serotype 5.