Skip to main content
. 2018 Oct 20;141(11):3249–3261. doi: 10.1093/brain/awy254

Figure 2.

Figure 2

Activity during viewing neutral and angry faces in Tourette syndrome participants and controls. The insula is hyperactive in Tourette syndrome for both facial expressions. (A) F-test of all effects, (B) F-test of all effects thresholded at more liberal threshold of P < 0.001 and minimum cluster size of 10 voxels, additionally showing the amygdala and insula, (C) controls neutral, (D) controls angry, (E) Tourette syndrome neutral, (F) Tourette syndrome angry. All images thresholded at P < 0.05 cluster-wise FDR (cluster-forming threshold P < 0.001) unless specified. (G–K) Contrast estimate effect size plots (pink bar represents 90% confidence interval) for the OFA (G), FFA (H), amygdala (I), IFG (J), and insula (K), respectively, for (left-to-right) controls neutral (CN), controls angry (CA), Tourette syndrome neutral (TS N), Tourette syndrome angry (TS A), plotted at co-ordinates given in G-K. Unthresholded statistic images are available at https://neurovault.org/collections/4167/.