Table 4.
Comparison of clinical characteristics between POAG and NTG patients
| Variables | POAG patients (n = 24) | NTG patients (n = 13) | Statistical value | P |
|---|---|---|---|---|
| Age (years) | 51.46 ± 12.04 | 48.23 ± 13.39 | 0.749* | 0.459 |
| Gender (male/female), n | 16/8 | 8/5 | NA | 0.515‡ |
| Right eyes/left eyes, n | 11/13 | 5/8 | 0.187† | 0.468 |
| BCVA (logMAR) | 0.05 ± 0.07 | 0.04 ± 0.07 | NA | 0.766§ |
| Spherical equivalent (D) | −1.90 ± 2.31 | −2.13 ± 2.15 | NA | 0.814§ |
| Pupil diameters (mm) | 3.42 ± 0.50 | 3.54 ± 0.52 | NA | 0.561§ |
| SAP-MD (dB) | −3.91 ± 1.18 | −3.73 ± 1.44 | NA | 0.695§ |
| SAP-MD of the other eye (dB) | −5.27 ± 4.50 | −5.04 ± 3.35 | NA | 0.626§ |
| OCT-thickness change in RNFL (μm) | ||||
| Temporal superior quadrant | −42.78 ± 32.35 | −27.08 ± 28.93 | NA | 0.085§ |
| Temporal inferior quadrant | −49.78 ± 28.14 | −43.83 ± 32.08 | NA | 0.668§ |
| Baseline IOP (mmHg) | 15.38 ± 3.08 | 16.54 ± 2.26 | NA | 0.404§ |
| CCT (μm) | 530.05 ± 30.24 | 517.91 ± 13.79 | NA | 0.197§ |
| icVEP-SNR | 0.92 ± 0.53 | 0.84 ± 0.64 | NA | 0.519§ |
| Sensitivity of icVEP | 15/24 | 8/13 | NA | 0.613‡ |
*Independent-sample t-test, †Chi-square test, ‡Fisher’s exact test, §Mann–Whitney U-test. 1 mmHg = 0.133 kPa. BCVA: Best-corrected visual acuity; CCT: Central corneal thickness; icVEP: Isolated-check visual evoked potential; IOP: Intraocular pressure; logMAR: Logarithm of the minimum angle of resolution; MD: Mean deviation; OCT: Optical coherence tomography; NTG: Normal-tension glaucoma; POAG: Primary open-angle glaucoma; RNFL: Retinal nerve fiber layer; SAP: Standard automated perimetry (HFA 30-2 SITA); SNR: Signal-to-noise ratio; HFA: Humphrey Field Analyzer; NA: Not available.