Figure 2.

Airway responsiveness in different groups. (a) Rrs in the control, OVA, OVA/PM, and PM groups at different concentrations of aerosolized Mch. (b) R_N in the four groups. (c) G in the four groups. (d) H in the four groups. Values are represented as the mean ± SD. Based on one-way ANOVA, followed by LSD multiple range tests, comparing with control group, a significant difference is indicated by *P < 0.001, ^†P < 0.01, and ^‡P < 0.05. Comparing with PM group, a significant difference is indicated by ^§P < 0.01 and ^||P < 0.05. Comparing with OVA group, a significant difference is indicated by ^¶P < 0.01 and **P < 0.05 (n = 6 per group). Rrs: Respiratory system resistance; R_N: Airway resistance; G: Tissue damping; H: Tissue elasticity; Mch: Methacholine; PM: Particulate matter; OVA: Ovalbumin; SD: Standard deviation; ANOVA: Analysis of variance; LSD: Least significant difference.