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. 2018 Oct 20;131(20):2461–2473. doi: 10.4103/0366-6999.243551

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Copyright: © 2018 Chinese Medical Journal

This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

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Comparison of the changes in lung tissues of mice in different groups (hematoxylin and eosin, ×200). The control group had intact terminal bronchioles and alveolar epithelia and showed no inflammation. The OVA group showed hyperplasia of smooth muscles of the small bronchi (black arrow), hyperplasia of lymphatic follicles (star), and infiltration of eosinophils (white arrow). The OVA/PM group displayed mild loss of tracheal epithelial cells, widening of the alveolar septa (black arrows), infiltration of inflammatory cells, and hyperplasia of smooth muscles of the small bronchi (stars). The PM group displayed the presence of inflammatory cells in peribronchiolar regions (black arrow) and substantial alveolar epithelial hyperplasia (stars). PM: Particulate matter; OVA: Ovalbumin.