Table 1.

Oncomirs in pathogenesis of renal cell carcinoma [1–40]

MicroRNA	Target	Pathway/mechanism
miR-7		Cell migration, proliferation and apoptosis
miR-15a-5p		Cell proliferation, migration, invasion and apoptosis
miR-17-5p	VEGF-A, EGLN3	Cell cycle, migration, proliferation, and invasion, modulation of the differentiation of mesenchymal stem cells
miR-21	TORC1, FasL, TIMP3, TCF21, PDCD4, TPM1.	Akt/TORC1/KISS1/ PTEN/Akt/IKKβ and NFκB-dependent cyclin D1 expression/Activation of caspase pathway/ cell proliferation and cell apoptosis
miR-23b	POX	HIF/apoptosis
miR-28-5p	Mad2	VHL/mitotic checkpoint function/chromosomal instability
miR-29b	KIF1B	Apoptosis, proliferation and invasion ability
miR-30b		Cell proliferation, invasion, migration and apoptosis
miR-106b		Cell proliferation, migration and apoptosis
miR-122	mTOR, OCLN, Sprouty2	PI3K/Akt/Cell proliferation, invasion and migration
miR-142-3p		Cellular migration, proliferation and apoptosis
miR-155	BACH1, E2F2	Cell proliferation, migratory activity and apoptosis
miR-195-3p		Cell proliferation, migration, invasion and apoptosis
miR-203a	GSK-3β	Cell proliferation, migration, and apoptosis
miR-210	ISCU1/2	VHL/HIF1α/centrosome amplification/ migratory and invasive potential of ACHN metastatic RCC cells
miR-217		HIF-1α/AXL/ LncRNA HOTAIR/ proliferation, migration, EMT process and apoptosis
miR-224	VHL, SMAD4, SMAD5, DIO1	VHL/ HIF1α/Tissue
hypothyroidism in RCC
miR-590-5p	PBRM1	Inhibition of G1/S transition /cell proliferation and invasion