Table 3.
MicroRNAs associated with renal cell carcinoma prognosis [1–40]
| MicroRNA | Pathway/mechanism |
|---|---|
| miR-9 | Cancer development and metastatic recurrence |
| miR-19a | Poor prognosis |
| miR-21 | Disease-free and overall survival rates, stage and grade, advanced clinic-pathological features and poor prognosis |
| miR-21/10b ratio | Disease severity and survival, poor prognosis in metastasis-free patients |
| miR-23b/27b cluster | Good overall survival |
| miR-27a-3p | Predictive factor for recurrence |
| miR-100 | Advanced tumor T stage, presence of metastasis, overall and tumor-specific survival |
| miR-106 | Early metastasis after nephrectomy |
| miR-124-3 | Advanced tumors and disease recurrence |
| miR-126 | Cancer-specific survival |
| miR-155 | Poor clinical outcomes |
| miR-187 | Lower survival rates |
| miR-217 | Lower survival rates |
| miR-221 | Poor overall survival |
| miR-321 | Tumor proliferation and survival rates |
| miR-424 | Tumor proliferation and survival rates |
| miR-429 | Linked to metastasis and poor prognosis |
| miR-486 | Cancerspecific mortality after nephrectomy |
| miR-497 | Poor prognosis |
| miR-630 | Lower overall survival |
| miR-1236 | Favorable survival |