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. 2018 Sep 25;4(10):1344–1351. doi: 10.1021/acscentsci.8b00383

Figure 3.

Figure 3

Generality of like-charge attraction at the membrane interface. (A) Schematic of the cell entry of structures including TDN-13, TDN-20, TDN-32, TDN-20d, and 6-helix. (B) PAGE electrophoresis characterization of the structures. (C) Representative simulation snapshots of DNA nanostructures attacking the cell membrane. (D) Representative landing spots of the structures on the cell membrane in typical simulations. (E) Cell entry efficiency of DNA nanostructures (green, simulation; blue, cytometric measurements. *, p < 0.05).