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. 2018 Sep 19;20:1092–1105. doi: 10.1016/j.nicl.2018.09.011

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — T2-weighted MRI Sections showing hyperintense regions in SOD1^G93A mice.

T2-weighted MRI showing hyperintense contrast in the brainstem region compared to surrounding regions in a 140 day old SOD1^G93A mouse. (A) Left: Sagittal sections: arrow shows hyperintensity in the brainstem nucleus Nc. XII (hypoglossal). Right: Sagittal sections: arrows show hyperintensities in the brainstem nuclei Nc V (trigeminal), Nc VII. (B) Coronal section: white arrows show bilateral hyperintensities in Nc V (trigeminal). Yellow arrow: hyperintensity in Nc XII (hypoglossal). (C) Coronal section: arrows show bilateral hyperintensities in Nc VII (facial).