Correlation between neurometabolite concentrations in SOD1G93A hindbrain.
Correlation between neurometabolite concentrations in the hindbrain of SOD1G93A mice for all time-points (30, 60, 70, 90, 110, 120, 140 days postpartum). (A) Correlation of regional glutamate and NAA concentrations across mouse age. The resulting slope in linear fit is represented by the dashed black line (R2 = 0.837). (B) Correlation between myo-Inositol versus NAA concentrations (R2 = 0.819). (C) Relation between glutamine and NAA concentrations (R2 = 0.898). (D) Correlation between creatine and NAA concentrations (R2 = 0.965). (E) Correlation between creatine and glutamate (R2 = 0.791) concentrations. Abbreviation: NAA, N-acetylaspartate; tCr, total creatine; mIns, myo-inositol;Glu, glutamate;