Table 1.
Metabolite Concentration (mean ± S.D in mmol/l) |
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Model | Age | Location | NAA | tCr | Glu | Gln | mIns | Taurine |
SOD | P30 | Hindbrain | 9.27 ± 0.79 | 7.45 ± 0.43 | 8.15 ± 0.73 | 3.87 ± 0.57 | 3.50 ± 0.39 | 2.23 ± 0.32 |
Motor cortex | 8.77 ± 0.88 | 6.68 ± 0.79 | 12.38 ± 1.50 | 3.01 ± 0.44 | 2.02 ± 0.47 | 7.82 ± 0.65 | ||
WT | Hindbrain | 9.42 ± 0.74 | 7.40 ± 0.20 | 8.30 ± 0.87 | 3.97 ± 0.47 | 3.04 ± 0.57 | 1.89 ± 0.85 | |
Motor cortex | 9.21 ± 1.12 | 7.21 ± 0.72 | 13.14 ± 1.98 | 3.54 ± 0.32 | 2.15 ± 0.76 | 8.12 ± 0.57 | ||
SOD | P110 | Hindbrain | 8.48 ± 0.81 | 6.47 ± 0.61 | 8.47 ± 1.05 | 2.59 ± 0.64 | 3.10 ± 1.03 | 2.50 ± 023 |
Motor cortex | 8.93 ± 0.78 | 7.11 ± 0.65 | 13.05 ± 0.87 | 3.23 ± 0.35 | 2.24 ± 0.36 | 9.45 ± 0.70 | ||
WT | Hindbrain | 9.43 ± 1.02 | 8.22 ± 0.59 | 9.13 ± 1.29 | 3.54 ± 0.36 | 3.24 ± 0.59 | 2.45 ± 0.14 | |
Motor cortex | 8.84 ± 0.92 | 7.68 ± 0.53 | 11.68 ± 1.80 | 3.10 ± 0.42 | 1.97 ± 0.89 | 8.35 ± 0.84 | ||
SOD | P140 | Hindbrain | 6.22 ± 0.49 | 5.23 ± 0.57 | 6.77 ± 0.61 | 2.91 ± 0.75 | 5.20 ± 0.55 | 2.36 ± 0.13 |
Motor cortex | 6.29 ± 0.73 | 6.68 ± 0.79 | 9.62 ± 1.26 | 3.21 ± 0.33 | 2.32 ± 0.61 | 10.03 ± 0.63 | ||
WT | Hindbrain | 10.05 ± 0.58 | 7.89 ± 0.78 | 9.24 ± 0.74 | 3.34 ± 0.42 | 3.45 ± 0.72 | 2.01 ± 0.35 | |
Motor cortex | 9.21 ± 0.47 | 7.45 ± 0.87 | 12.85 ± 0.84 | 3.12 ± 0.25 | 2.04 ± 0.63 | 8.73 ± 0.65 |