Table 4.
Coordinates for brain areas showing functional connectivity to the bilateral V5/MT and to the left TVSA during visual-speech recognition.
| Seed region: right V5/MT | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Region | x | y | z | Z | x | y | z | Z | |
| Control | ASD | ||||||||
| V5/MT | l | −45 | −73 | 5 | 4.86 | −39 | −73 | 2 | 3.40 |
| −33 | −76 | 2 | 3.43 | ||||||
| TVSA |
l | −51 | −46 | 8 | 3.88 | – | |||
| −48 |
−43 |
5 |
3.67 |
||||||
| IFG | l | −54 | 11 | 11 | 3.73 | – | |||
| PCG | l | −51 | 2 | 50 | 3.65 | – | |||
| SMA | l | −3 | 8 | 59 | 4.17 | – | |||
| r | 0 | 5 | 68 | 3.04 | |||||
| 6 | 8 | 71 | 3.01 | ||||||
| Control > ASD | ASD > Control | ||||||||
| TVSA | l | −48 | −43 | 2 | 3.71 | – | |||
| IFG | l | −54 | 11 | 11 | 3.35 | – | |||
| Seed region: left V5/MT | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | ASD | ||||||||
| V5/MT | r | 51 | −64 | −7 | 3.64 | – | |||
| TVSA | l | −57 | −40 | 5 | 2.98 | – | |||
| IFG | l | −57 | 11 | 17 | 3.09 | – | |||
| PCG | – | – | |||||||
| SMA | l | −9 | 8 | 56 | 3.04 | – | |||
| Control > ASD | ASD > Control | ||||||||
| – | – | ||||||||
| Seed region: left TVSA | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | ASD | ||||||||
| V5/MT |
r | 48 | −61 | 5 | 5.45 | – | |||
| 45 | −70 | −1 | 4.77 | ||||||
| 48 | −67 | −4 | 4.57 | ||||||
| l |
−45 |
−73 |
2 |
4.82 |
– |
||||
| IFG | l | −60 | 11 | 20 | 3.87 | – | |||
| PCG | l | −48 | −1 | 47 | 4.61 | – | |||
| SMA | l | −9 | 8 | 56 | 3.25 | – | |||
| Control > ASD | ASD > Control | ||||||||
| V5/MT | l | −48 | −67 | −1 | 3.45 | – | |||
Coordinates represent local connectivity maxima in MNI space (in mm) for the whole brain. Clusters are reported that reached significance at p = .007 FWE corrected (peak-level) for the respective ROI and Holm-Bonferroni corrected for seven ROIs, and which cluster size contained more than 5 voxels. Anatomically, regions were labeled using a standard anatomical atlas (Harvard-Oxford cortical and subcortical structural atlases (Desikan et al., 2006) and Jülich histological (cyto- and myelo-architectonic) atlas (Eickhoff et al., 2007)) implemented in FSL (Smith et al., 2004; http://www.fmrib.ox.ac.uk/fsl/fslview). V5/MT = visual area 5/ middle temporal area; TVSA = temporal visual speech area; IFG = inferior frontal gyrus; PCG = precentral gyrus; SMA = supplementary motor area; Z indicates the statistical value.