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. 2018 Oct 26;21(Suppl Suppl 8):e25187. doi: 10.1002/jia2.25187

Abstract P264 – Table 1. PK parameters of HIV ARVs and HCV DAAs when co‐administered

B/F/TAF+LDV/SOF BIC FTC TAFa TFV SOF GS‐331007 LDV
AUCtau 67%↑
Cmax 43%↑
Ctau NR 81%↑ NR
B/F/TAF+SOF/VEL/VOX BIC FTC TAFa TFV SOF GS‐331007 VEL VOX
AUCtau 58%↑ 67%↑
Cmax 28%↑ 51%↑
Ctau NR 74%↑ NR

Note: The % change is presented in the table based on calculated %GLSM ratios; 90% CI of the GLSM ratios were within (), extended above (↑) the predefined lack of PK alteration boundaries of 70% to 143%. aAUClast presented for TAF. NR = not reported.