Abstract P301 – Table 2. Frequency of gp120 mutations according to CRT and subtype
| Substitution | R5 | Non‐R5 | p value | B | Non‐B | p value |
|---|---|---|---|---|---|---|
| L116 wt | 261 (98.1) | 58 (98.3) | 0.99 | 208 (98.6) | 111 (97.3) | 0.58 |
| L116P | 1 (0.37) | 0 (0.0) | 1 (0.47) | 0 (0.0) | ||
| L116 other | 4 (1.5) | 1 (1.7) | 2 (0.93) | 3 (2.7) | ||
| S375 wt | 247 (80.4) | 52 (69.3) | 0.014 | 175 (72.0) | 124 (89.2) | <0.001 |
| S375 H/M/T | 39 (12.7) | 20 (26.7) | 50 (20.6) | 9 (6.5) | ||
| S375 other | 21 (6.8) | 3 (4.0) | 18 (7.4) | 6 (4.3) | ||
| M426 wt | 171 (72.2) | 26 (57.8) | 0.10 | 104 (57.5) | 93 (92.1) | <0.001 |
| M426L | 16 (6.8) | 3 (6.7) | 15 (8.3) | 4 (4.0) | ||
| M426 other | 50 (21.1) | 16 (35.6) | 62 (34.3) | 4 (4.0) | ||
| M434 wt | 185 (94.2) | 40 (95.2) | 0.79 | 149 (94.9) | 76 (93.8) | 0.73 |
| M434I | 6 (3.1) | 1 (2.4) | 5 (3.2) | 2 (2.5) | ||
| M434 other | 5 (2.6) | 1 (2.4) | 3 (1.9) | 3 (3.7) | ||
| M475 wt | 92 (95.8) | 16 (100) | 1.0 | 65 (98.5) | 43 (93.5) | 0.16 |
| M475I | 3 (3.1) | 0 (0.0) | 1 (1.5) | 2 (4.3) | ||
| M475L | 1 (1.0) | 0 (0.0) | 0 (0.0) | 1 (2.2) |
Results are presented as number (percentage) of strains. wt = wild type.