Table 2.
Effects of therapeutic and supra-therapeutic doses of CGV on antioxidant indices in rat ovaries
| Treatment | GSH | SOD | CAT | GST | MDA |
|---|---|---|---|---|---|
| Control | 21.94 ± 1.77 | 17.9 ± 0.13 | 12.47 ± 1.46 | 6.3 ± 0.05 | 1.13 ± 0.02 |
| 14.3 | 59.68 ± 3.77** (− 172) | 13.21 ± 1.06 (26.2) | 16.48 ± 2.58* (− 32.2) | 3.95 ± 1.15 (37.3) | 1.13 ± 0.22 (0.0) |
| 28.6 | 61.72 ± 5.19** (− 181.3) | 13.78 ± 2.17 (23) | 16.89 ± 1.04* (− 35.4) | 3.98 ± 1.49 (36.8) | 0.93 ± 0.13 (17.7) |
| 1000 | 18.31 ± 1.00 (16.5) | 13.9 ± 0.12 (22.3) | 12.91 ± 0.67 (− 3.5) | 3.7 ± 0.03 (41.3) | 1.5 ± 0.04* (− 32.7) |
| 2000 | 21.62 ± 1.96 (1.5) | 12.8 ± 0.12 (28.5) | 12.54 ± 0.41 (− 0.6) | 3.4 ± 0.03 (46.0) | 1.45 ± 0.04*(− 28.3) |
| 3000 | 20.37 ± 1.51 (7.2) | 16.0 ± 0.04 (10.6) | 13.41 ± 0.47 (− 7.5) | 4.2 ± 0.01 (33.3) | 1.57 ± 0.02*(− 38.9) |
Data are expressed as mean ± SEM. n = 6.*p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg); Superoxide dismutase; GSH Reduced glutathione (μmol/mg protein), SOD Superoxide dismutase (μmol/min/mg protein), Catalase (μmol/ml/mg protein), GST Glutathione S-transferase (μmol/ml/mg protein), MDA Malondialdehyde (nmol/mg protein)