Table 3.
Effects of therapeutic and supra-therapeutic doses of CGV On Serum Biochemical Indices in Male Rats
| Treatment/ mg/kg | UREA (mg/l) | CREAT (mmol/l) | CHOL (mmol/l) | TG (mol/l) | HDL (mmol/l) | LDL (mmol/l) | ALP (U/l) | ALB (U/l) | TP (U/l) |
|---|---|---|---|---|---|---|---|---|---|
| Control | 10.55 ± 0.86 | 4.43 ± 0.76 | 1.64 ± 0.09 | 0.91 ± 0.16 | 0.57 ± 0.05 | 0.35 ± 0.04 | 18.90 ± 1.82 | 27.52 ± 1.81 | 13.71 ± 0.02 |
| 14.3 | 10.10 ± 0.21 (4.3) | 4.11 ± 1.04 (7.2) | 1.44 ± 0.22 (12.2) | 0.89 ± 0.07 (2.1) | 0.58 ± 0.02 (− 1.8) | 0.33 ± 0.05 (5.7) | 18.43 ± 2.02 (2.5) | 26.25 ± 1.70 (4.6) | 12.3 ± 0.47 (10.3) |
| 28.6 | 10.90 ± 0.25 (3.3) | 4.21 ± 1.03 (5.0) | 1.38 ± 0.08 (15.9) | 0.78 ± 0.11 (14.3) | 0.52 ± 0.04 (8.8) | 0.32 ± 0.03 (8.6) | 18.06 ± 3.93 (4.4) | 27.76 ± 2.05 (− 0.9) | 11.47 ± 0.15 (16.3) |
| 1000 | 9.58 ± 0.28 (9.2) | 3.65 ± 0.99 (17.6) | 1.57 ± 0.12 (4.3) | 0.76 ± 0.07 (16.5) | 0.55 ± 0.02 (3.5) | 0.35 ± 0.02 (0) | 18.32 ± 3.02 (3.1) | 30.55 ± 3.70 (11) | 13.3 ± 1.47 (3) |
| 2000 | 9.50 ± 0.69 (10.0) | 4.95 ± 2.13 (− 11.7) | 1.57 ± 0.18 (4.3) | 0.77 ± 0.11 (15.4) | 0.59 ± 0.03 (− 3.5) | 0.37 ± 0.07 (− 5.7) | 17.66 ± 3.93 (6.6) | 28.45 ± 3.05 (− 3.4) | 5.47 ± 0.25* (60.1) |
| 3000 | 9.90 ± 0.80 (10.1) | 8.82 ± 1.75* (− 99.1) | 1.61 ± 0.21 (1.8 s) | 0.75 ± 0.07 (17.5) | 0.56 ± 0.03 (1.8) | 0.4 ± 0.08 (− 14.3) | 18.75 ± 1.8 (0.8) | 28.50 ± 3.12 (− 3.6) | 5.87 ± 1.11* (57.2) |
Data are expressed as mean ± SEM. n = 6. *p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg). CREA Creatinine, CHOL cholesterol, TG Triglycerides, HDL High density lipoprotein, LDL Low density lipoprotein, ALP Alkaline phosphatase, ALB Albumin, TP total protein