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. 2018 Oct 25;16:295. doi: 10.1186/s12967-018-1670-9

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — ¹⁸FDG uptake during doxorubicin treatment in the myocardium and in the longissimus thoracis muscle. Boxes are median and interquartile ranges of left ventricular and skeletal muscle ¹⁸FDG standardized uptake values (SUV) at the indicated ¹⁸FDG positron emission tomography (¹⁸FDG-PET) scans. Vertical bars indicate the highest and lowest SUV at each time point. Repeated measures ANOVA P for trend = 0.0007 and 0.02 for SUV in the heart and longissimus thoracis, respectively. STAGING: ¹⁸FDG-PET before treatment; INTERIM: ¹⁸FDG-PET after 2 cycles of doxorubicin; EOT: ¹⁸FDG-PET at the end of treatment