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. 2018 Oct 25;16:295. doi: 10.1186/s12967-018-1670-9

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Left ventricular ejection fraction according to categories of ¹⁸FDG uptake in patients with echocardiography at follow-up. Left ventricular ejection fraction (LVEF), as assessed by echocardiography performed after completion of anthracycline chemotherapy, in patients with myocardial ¹⁸FDG standardized uptake values (LV-SUV) below or above the median value (low and high, respectively) measured at each ¹⁸FDG positron emission tomography (¹⁸FDG-PET) scan. For each PET time point, LVEF was compared between patients with LV-SUV below vs. above the median value by unpaired t-test. * indicates P < 0.05. LV-SUV^STAGING: LV-SUV at the ¹⁸FDG-PET scan before treatment; LV-SUV^INTERIM: LV-SUV at the ¹⁸FDG-PET performed after 2 cycles of doxorubicin; LV-SUV^EOT: LV-SUV at the ¹⁸FDG-PET performed at the end of chemotherapy