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drug toxicity and adverse events
| Adverse events | No toxicity (grade0–2) (N = 109) |
Toxicity(grade 3–4) (N = 102) |
|---|---|---|
| Hematological | ||
| Leucopenia | 98 | 95 |
| Neutropenia | 93 | 90 |
| Anemia | 8 | 1 |
| Thrombocytopenia | 2 | 1 |
| Gastrointestinal | ||
| Nausea | 47 | 0 |
| Vomiting | 86 | 18 |
| Diarrhea | 16 | 13 |
| Skin rash | 6 | 2 |
| hepatotoxicity | 3 | 0 |
| Renal toxicity | 1 | 0 |
