Fig. 3.

Frequency of the different clinical severity scores at first, second and all following bouts in 70 autoimmune thrombotic thrombocytopenic purpura (iTTP) patients. During the first iTTP manifestation, the proportion of severe episodes was higher than during 1st relapse and all subsequent relapses. Absolute numbers in a total of 219 bouts: 1st manifestation: laboratory (0): n  = 1, mild (1): n  = 11, moderate (2): n  = 22, severe (3): n  = 34; 1st relapse: laboratory (0): n  = 2, mild (1): n  = 19, moderate (2): n  = 8, severe (3): n  = 7, death (4): n  = 1; all further relapses: laboratory (0): n  = 18, mild (1): n  = 64, moderate (2): n  = 11, severe (3): n  = 14, death (4): n  = 1.