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. 2018 Jul 4;118(8):1397–1408. doi: 10.1055/s-0038-1661393

Fig. 2.

Fig. 2

Multimeric pattern of von Willebrand factor (VWF) after separation on 0.8% agarose gel and the corresponding densitometric curves. ( A ) Characteristic plasma sample of a patient with acute decompensation (AD), stable (ST) cirrhosis and healthy control. The presence of ultra-large molecular weight multimers (ULMWM) is seen in the sample of the AD patient. No ULMWM can be seen in the sample of ST cirrhosis or healthy control. The dotted lines across the lanes represent critical separation on the distribution ladder according to the number of the corresponding bands. The critical separation lines: #1 = 1 dimer; #6 = 6 dimers and #10 = 10 dimers. Dimers < 6 are defined as low molecular weight multimers (LMWM), dimers between 6 and 10 defined as intermediate molecular weight multimers (IMWM) and dimers > 10 defined as high molecular weight multimers (HMWM) including ULMWM. ( B ) The corresponding densitometric curves indicated with different lines and areas as marked at the bottom of A .