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. 2018 Oct 18;11:7187–7196. doi: 10.2147/OTT.S180962

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© 2018 Su et al. This work is published and licensed by Dove Medical Press Limited

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SPHK1 mRNA overexpression in NB cells and human NB tissues.

Notes: (A) SPHK1 mRNA expression was detected in NB cells. The SPHK1 mRNA level was significantly upregulated in SH-SY5Y and SK-N-SH cells compared with HUVEC cells. ^**P<0.01 vs HUVEC cells. (B) SPHK1 mRNA expression was detected in 29 human NB tissues and MANT. The SPHK1 mRNA level was significantly upregulated in NB tissues compared with MANT. ^**P<0.01 vs MANT.

Abbreviations: HUVEC, human umbilical vein endothelial cells; MANT, matched adjacent nontumorous tissues; NB, neuroblastoma; SPHK1, sphingosine kinase 1.