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. 2018 Oct 18;11:7187–7196. doi: 10.2147/OTT.S180962

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© 2018 Su et al. This work is published and licensed by Dove Medical Press Limited

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Effect of SPHK1 knockdown by siRNA on the migration and invasion of SH-SY5Y and SK-N-SH cells. Analysis of migration capability of SH-SY5Y (A) and SK-N-SH (B) cells. Analysis of invasion capability of SH-SY5Y (C) and SK-N-SH (D) cells.

Notes: Both the migrated and invaded number of SH-SY5Y and SK-N-SH cells with SPHK1 knockdown was significantly decreased compared with negative control or blank control. **P<0.01 vs negative control or blank control group.

Abbreviation: SPHK1, sphingosine kinase 1.