Table 1.
Baseline demographic and laboratory characteristics of patients with RA included in this data set
| Patient characteristics | Neutropaenic n=58 |
Non–neutropaenic n=713 |
P values |
| Demographic | |||
| Age,* mean±SD | 57.7±14.1 | 58.8±13.4 | 0.538 |
| Female gender, n (%) | 47 (81.0) | 460 (64.5) | 0.010 |
| Total follow-up (months), median (range) | 18 (6–48) | 18 (6–48) | 0.139 |
| Smoking, n (%) | 6 (10.3) | 188 (26.4) | 0.007 |
| Alcohol consumption, n (%) | 40 (69.0) | 421 (57.9) | 0.127 |
| Laboratory | |||
| Anaemia,† n (%) | 7/55 (12.7) | 142/702 (20.2) | 0.218 |
| Thrombocytopaenia,‡ n (%) | 0/55 (0.0) | 0/702 (0.0) | 1.000 |
| Leucopaenia,§ n (%) | 1/55 (1.8) | 3/702 (0.4) | 0.261 |
| Lymphopaenia,¶ n (%) | 4/55 (7.2) | 40/702 (5.7) | 0.520 |
| Neutrophils number, mean±SD (×10^9/L)** | 4.29±2.12 | 5.89±2.15 | <0.0001 |
| RF-positive, n (%) | 27/35 (77.1) | 284/428 (67.1) | 0.262 |
| Anti-CCP-positive, n (%) | 35/46 (74.4) | 410/587 (69.8) | 0.620 |
| Baseline DAS28, mean±SD | 4.76±1.51 | 5.04±1.38 | 0.310 |
*Age at the time of RA diagnosis.
†Haemoglobin <135 g/L for men and haemoglobin <120 g/L for women.
‡Platelets <100×10^9/L
§White cell count: <4×109/L.
¶Lymphocytes: <1×109/L.
**n=53 (5 patients had neutropaenia at baseline).
CCP, Cyclic Citrullinated Peptide; DAS28, Disease Activity Score in 28 joints; RA, rheumatoid arthritis; RF, rheumatoid factor.