Figure 3.

Interactome analysis reveals known and novel interactions for A20. Affinity purification mass spectrometry and BioID analysis of A20 identified 98 high-confidence protein–protein interactions (known interactions are shown with green lines, novel interaction detected on this study with blue and known prey–prey interactions with a dashed line). The interacting proteins are grouped based on their molecular functions/complexes. Interactions, which are lost with the p.(Lys91*) mutation, are illustrated with red node fill colour.