Table 1.
Comparison of clinical characteristics and waitlist mortality and post-transplant survival among liver transplant registrants listed for SAH, and APAP as well as non-APAP related acute liver failure from 2011 to 2016
| Waitlist outcomes | ||||
|---|---|---|---|---|
| SAH (n = 186) | APAP (n = 241) | Non-APAP (n = 690) | P -value | |
| Median age [IQR] | 46.6 [36–56] | 34.7 [25–44] | 55.2 [51–62] | <0.001 |
| Gender (%) | <0.001 | |||
| Male | 121 (65.1%) | 48 (19.9%) | 506 (73.3%) | |
| Ethnicity (%) | <0.001 | |||
| Caucasian | 141 (75.8%) | 194 (80.5%) | 361 (52.3%) | |
| African-American | 8 (4.3%) | 15 (6.2%) | 89 (12.9%) | |
| Hispanic | 26 (14.0%) | 21 (8.7%) | 98 (14.2%) | |
| Other | 11 (5.9%) | 11 (4.6%) | 142 (20.6%) | |
| Median MELD score, [IQR] | 32 [25–40] | 34 [29–41] | 21 [11–31] | <0.001 |
| MELD score >26 (%) | 138 (74.2%) | 206 (85.5%) | 209 (30.3%) | <0.001 |
| Median total Bilirubin, [IQR] | 20.0 [6.3–29.3] | 5.8 [1.8–6.4] | 8.4 [1.2–11.2] | <0.001 |
| Median INR [IQR] | 2.2 [1.6–2.5] | 5.0 [2.8–6.4] | 2.1 [1.2–2.3] | <0.001 |
| Severe HE (%) | 35 (18.8%) | 36 (14.9%) | 25 (3.6%) | <0.001 |
| 7-Day waitlist mortality %, (95% CI) | 1.6 (2.1–4.4) | 8.0 (4.9–12.0) | 1.3 (0.7–2.4) | <0.001 |
| 15-Day waitlist mortality %, (95% CI) | 4.5 (2.1–8.2) | 8.0 (4.9–12.0) | 2.3 (1.4–3.7) | <0.001 |
| 30-Day waitlist mortality %, (95% CI) | 6.9 (3.7–11.3) | 11.4 (6.4–18.0) | 3.3 (2.1–4.8) | 0.05 |
| LT surgeries (%) | 126 (67.7%) | 88 (36.3%) | 402 (58.2%) | <0.001 |