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. 2018 Sep 17;53(6):2473–2487. doi: 10.3892/ijo.2018.4563

Figure 12.

Figure 12

Analysis of PI-RI. The two splicing events of the RI type from which the PI-RI was generated, were identified from DFS-associated splicing events by multivariate Cox regression analysis. (A) Illustration of RI site. (B) Scatter plot of time of DFS vs. cancer status of PRAD patients. (C) PI value curve for patients with PRAD. (D) Time-dependent receiver operating characteristic curve of PI for predicting the tumor status after five years. (E) Kaplan-Meier curve of PI for evaluating the DFS time of PRAD patients stratified by median PI value into low and high group. PI-RI, prognostic index based on the Retained Intron type of splicing events; PRAD, prostate adenocarcinoma; AUC, area under curve; DFS, disease-free survival; CCL14, C-C motif chemokine ligand 14; CSAD, cysteine sulfinic acid decarboxylase.