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CD147 and IGFBP2 overexpression in melanoma tissues. (A) Representative immunohistochemical staining of CD147- or IGFBP2-positive cells in nevus (n=15), PMM (n=128) and MMM (n=64) tissues. Magnification, ×100. (B) Comparison of the CD147- and IGFBP2-positive area (%) in nevus and melanoma microassay tissue. Semi-quantitation was performed using Image-Pro Plus 6.0 software. **P<0.05 MMM vs. PMM or nevus. MMM, metastatic malignant melanoma; PMM, primary malignant melanoma.
