Table II.
Top 10 terms of molecular function (MF).
| Category | Term | Description | P-value | Gene |
|---|---|---|---|---|
| GOTERM_MF _DIRECT | GO:0005201 | Extracellular matrix structural constituent | 3.10E-04 | COL1A1, COL3A1, COL4A1, COL4A2, LAMC1 |
| GOTERM_MF _DIRECT | GO:0004252 | Serine-type endopeptidase activity | 9.49E-04 | C1QA, C1QB, C1QC, C1RL, C1R, C1S, C3 |
| GOTERM_MF _DIRECT | GO:0048407 | Platelet-derived growth factor binding | 1.24E-03 | COL1A1, COL3A1, COL4A1 |
| GOTERM_MF _DIRECT | GO:0005102 | Receptor binding | 1.60E-03 | ABCA1, FYB, TYROBP, F2R, C3, IDH1, HLA-B, HLA-F |
| GOTERM_MF _DIRECT | GO:0005178 | Integrin binding | 1.68E-03 | CD151, COL3A1, FN1, GFAP, LAMB2 |
| GOTERM_MF _DIRECT | GO:0001948 | Glycoprotein binding | 3.52E-03 | FLNA, GFAP, ITGB2, VIM |
| GOTERM_MF _DIRECT | GO:0005515 | Protein binding | 3.78E-03 | ABCA1, BARD1, CD151, CD163, DAB2, FYB, KIAA0101, RAB13, RAD51AP1, STEAP3, TEAD1, THOC2, TNFRSF1A, TYROBP, ZFP36L2, ANXA2, CALU, CHEK1, CLIC1, F2R, COL1A1, COL3A1, C3, CDK1, DTX3L, FN1, FLNA, GFAP, GBP1, HMG20B, IGFBP7, ITGB2, MCCC2, MCM5, MYOF, NOTCH2NL, PTX3, PTBP1, PTPRC, RNF135, SLC40A1, UHRF1, VIM |
| GOTERM_MF _DIRECT | GO:0042605 | Peptide antigen binding | 1.05E-02 | HLA-B, HLA-C, HLA-F |
| GOTERM_MF _DIRECT | GO:0098641 | Cadherin binding involved in cell-cell adhesion | 1.33E-02 | ARHGAP18, ANXA2, CALD1, CLIC1, FLNA, IDH1 |
| GOTERM_MF _DIRECT | GO:0046977 | TAP binding | 0.014459 | HLA-B, HLA-C |