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. 2018 Oct 1;53(6):2433–2444. doi: 10.3892/ijo.2018.4580

Table I.

Association between miR-103 and LATS2 expression levels with the clinicopathological characteristic of patients with hepatocellular carcinoma.

Variable Total no. of patients, n=120 (%) miR-103
P-value LATS2
P-value
Low expression High expression Low expression High expression
Age (years) 0.057 0.120
 <50 49 (40.8) 10 39 37 12
 ≥50 71 (59.2) 26 45 44 27
Sex 0.496 0.349
 Female 21 (17.5) 5 16 16 5
 Male 99 (82.5) 31 68 65 34
HBsAg 0.955 0.903
 Positive 76 (63.3) 15 61 51 25
 Negative 44 (36.7) 21 23 30 14
AFP (ng/ml) 0.01a 0.422
 <400 97 (80.8) 24 73 50 27
 ≥400 23 (19.2) 12 11 31 12
Cirrhosis 0.741 0. 903
 Yes 76 (63.3) 22 54 51 25
 No 44 (36.7) 14 30 30 14
Tumor size (cm) 0.007a 0.032a
 <5 48 (40) 21 27 27 21
 ≥5 72 (60) 15 57 54 18
Tumor multiplicity 0.228 0.992
 Single 77 (64.2) 26 51 52 25
 Multiple 43 (35.8) 10 33 29 14
Differentiation 0.318 0.383
 Well-moderate 53 (44.2) 17 36 38 15
 Poor-undifferentiated 67 (55.8) 19 48 43 24
Microscopic vascular invasion <0.001b 0.001a
 Yes 39 (32.5) 28 11 18 21
 No 81 (67.5) 8 73 63 18
Stage <0.001b 0.021a
 I–II 78 (65) 32 46 47 31
 III–IV (with metastasis) 42 (35) 4 38 34 8

Values in bold indicate statistical significance (aP<0.05 and bP<0.01).