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. 2018 Oct;59(12):5116–5124. doi: 10.1167/iovs.18-24455

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Copyright 2018 The Authors

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Temporal contrast sensitivity and visual acuity of grk1b and grk7a knockout larvae. Optokinetic response measurements of larval knockout zebrafish at 6 dpf. (A) Optokinetic gain as function of temporal frequency of a sinewave grating. A linear mixed model analysis of covariance found a significant effect of genotype when compared to wildtype for grk1^−/− (F_[1,209] = 32.9; P < 0.001) and grk7a^−/− (F_[1,193] = 21.4; P < 0.001) larvae. The accompanying table shows all means and standard errors from the graph. (B) Visual acuity measured in cycles/degree (cpd). P-values were obtained using the Bonferonni post hoc test following 1-way ANOVA. Error bars represent SEM.