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. 2018 Oct 25;13:53. doi: 10.1186/s13020-018-0211-z

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Correlation network analysis of 28 differential metabolites among Liver Qi Stagnation (LQS) and Heart and Spleen Deficiency (HSD) subtypes of MDD versus healthy controls. Green and red lines with ovals indicates negative and positive correlation, respectively. The ovals with half green and half red colors indicate mixed correlations. The oval size represents p value compared with healthy controls. Isobutyric acid (dark brown oral) has a significant difference between the two subtypes. B blood samples, U urine samples