Table 1.
Clinical manifestations and diagnostic criteria of TCM-based subtypes of MDD
| Liver Qi Stagnation (LQS) | Heart and Spleen Deficiency (HSD) | |
|---|---|---|
| Mood symptom characters | Depressed mood with frustration, nervousness, and/or irritability | Depressed mood with excessive pensiveness, suspicion, and/or timorousness |
| Somatic symptoms | A. Frequently sighing (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) B. Chest distension and/or hypochondriac pain (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) C. Abdominal bloating (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) D. Decreased appetite (0 = absent, 1 = mild, 2 = moderate, 3 = severe) E. Loose stool (0 = absent, 1 = mild, 2 = moderate, 3 = severe) F. Breast tenderness (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) G. Irregular menstruation (0 = normal, 1 = seldom, 2 = sometimes, 3 = frequent)a H. Menstrual pain (0 = absent, 1 = mild, 2 = moderate, 3 = severe)a |
A. Palpitation (0 = normal, 1 = seldom, 2 = sometimes, 3 = most times, 4 = all times) B. Forgetfulness (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) C. Insomnia or dream-disturbed sleep (0 = absent, 1 = sometimes, 3 = most times) D. Decreased appetite (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) E. Abdominal fullness (0 = absent, 1 = sometimes, 3 = most times) F. Loose stool or dysfunctional diarrhea (0 = absent, 1 = slight, 2 = mild, 3 = moderate, 4 = severe) G. Pale and sallow complexion (0 = normal, 1 = slightly apparent, 2 = mildly apparent; 3 = moderately apparent, 4 = very apparent) H. Tiredness (0 = absent, 1 = mild, 2 = moderate, 3 = severe) |
| Tongue and pulse | I. Red tongue body with thin and white coating (0 = normal, 1 = mildly apparent, 2 = moderately apparent, 3 = very apparent) J. Wiry pulse (0 = normal, 1 = slightly apparent, 2 = mildly apparent; 3 = moderately apparent, 4 = very apparent) |
I. Pale and tender or watery tongue body with white coating (0 = normal, 1 = slightly apparent, 2 = mildly apparent; 3 = moderately apparent, 4 = very apparent) J. Weak and thin pulse (0 = normal, 1 = slightly apparent, 2 = mildly apparent; 3 = moderately apparent, 4 = very apparent) |
| Diagnostic criteriab | [1]. Must have A, B, I, and J; at least one of D and E; and at least one of F, G, and H for women [2]. Total score of physical symptoms and tongue and pulse signs is not less than 10 |
[1]. Must have at least two of A, B and C; at least two of D, E and F; at least one of G and H; I and J [2]. Total score of physical symptoms and tongue and pulse signs is not less than 10 |