Regression coefficients from isotemporal substitution analyses: Standardised change in outcome (SD for BMI and abdominal fat distribution) by replacing 1-hour of sedentary and light intensity PA with light to vigorous intensity PA. Black lines: Analyses adjusted for age, smoking and fraction of weekend wear time, total hours spent on PA >1 METs. Grey lines: Analyses further adjusted for BMI
SAT: subcutaneous adipose tissue, VAT: visceral adipose tissue, WC: waist circumference (cm). SED: sedentary behavior, 1.00-1.5 METs, LPA: light physical activity >1.5-3.0 METs, MPA: moderate physical activity >3.0-6.0 METs, VPA: vigorous physical activity <6.0 METs.