Table 3. Prevalence ratios (95% confidence intervals) for being extremely concerned (vs. having lower levels of concern) about specific adverse outcomes ( n  = 519): 2016 .

	Age	Sex	Race	Initial treatment	Current treatment
	Per 10 y	Male vs. female	Non-white vs. white	DOAC vs. warfarin	DOAC vs. warfarin	No OAC vs. warfarin
Recurrent VTE
Model 1	0.85 (0.77, 0.94)	1.02 (0.71, 1.46)	1.18 (0.80, 1.73)
Model 2	0.86 (0.77, 0.95)	1.01 (0.71, 1.45)	1.16 (0.79, 1.71)	1.10 (0.86, 1.42)
Model 3	0.85 (0.77, 0.95)	1.02 (0.71, 1.46)	1.18 (0.80, 1.73)		1.01 (0.76, 1.33)	1.06 (0.77, 1.46)
Major bleeding a
Model 1	1.03 (0.91, 1.18)	0.95 (0.60, 1.50)	1.49 (0.92, 2.42)
Model 2	1.04 (0.91, 1.19)	0.95 (0.60, 1.50)	1.49 (0.92, 2.41)	1.19 (0.85, 1.68)
Model 3	1.11 (1.01, 1.22)	0.64 (0.43, 0.95)	0.92 (0.60, 1.40)		0.17 (0.10, 0.27)	0.45 (0.31, 0.65)
Moderate bleeding b
Model 1	0.95 (0.81, 1.12)	0.96 (0.54, 1.69)	1.93 (1.14, 3.26)
Model 2	0.96 (0.81, 1.13)	0.96 (0.54, 1.69)	1.93 (1.14, 3.27)	1.02 (0.67, 1.54)
Model 3	0.93 (0.79, 1.10)	0.95 (0.54, 1.68)	1.88 (1.11, 3.16)		0.77 (0.50, 1.19)	0.55 (0.29, 1.02)
Death c
Model 1	0.96 (0.86, 1.06)	1.14 (0.80, 1.63)	1.24 (0.81, 1.90)
Model 2	0.95 (0.85, 1.06)	1.14 (0.80, 1.64)	1.24 (0.81, 1.91)	0.96 (0.72, 1.28)
Model 3	0.94 (0.84, 1.05)	1.13 (0.79, 1.62)	1.25 (0.82, 1.91)		0.85 (0.64, 1.14)	0.52 (0.33, 0.82)

Abbreviations: DOAC, direct oral anticoagulant; OAC, oral anticoagulant; VTE, venous thromboembolism.

Note: Model 1: age (continuous per 10-year increments); sex (referent = female); race (referent = Caucasian).

Model 2: model 1 + initial treatment (referent = warfarin).

Model 3: model 1 + current treatment (referent = warfarin).

^aDescribed as bleeding into the head that causes permanent disability.

^bDescribed as bleeding that requires medical treatment.

^cDeath from any cause.