Table 2.
CSF markers before and after treatment. Comparison of difference of biomarkers between baseline and follow up within and between the two treatment groups
| Galantamine | Risperidone | ||||||
|---|---|---|---|---|---|---|---|
| Baseline M±SD | Follow-up M± SD | P Between group | Baseline M± SD | Follow-up M± SD | P Within group Galantamine | P Within group Risperidone | |
| Total Tau (pg/ml) | 731.8±430.39 | 728.9±414.89 | 0.96 | 755.4±460.1 | 749.7±568.4 | 0.930 | 0,878 |
| Aß1-42 (pg/ml) | 468.2±205.2 | 449.1±155.04 | 0.39 | 490.8±175.8 | 450.8±166.2 | 0,260 | 0,026 |
| Phosphorylated-Tau (pg/ml) | 103.2±63.38 | 90.8±39.63 | 0,147 | 94.9±56.20 | 89.1±49.92 | 0,147 | 0,210 |
| Aß40/42 ratio (pg/ml) | 0.52±0.266 | 0.51±0.210 | 0.91 | 0.54±0.240 | 0.53±0.203 | 0.425 | 0.207 |
Data are presented as means and standard deviations. Independent T-test was used to analyze effects between treatment groups. Depended T-test was used for analysis of within treatment group effects. Significant results considered at p<0.05