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. Author manuscript; available in PMC: 2018 Oct 26.
Published in final edited form as: J Alzheimers Dis. 2017;57(2):387–393. doi: 10.3233/JAD-160758

Table 2.

CSF markers before and after treatment. Comparison of difference of biomarkers between baseline and follow up within and between the two treatment groups

Galantamine Risperidone
Baseline M±SD Follow-up M± SD P Between group Baseline M± SD Follow-up M± SD P Within group Galantamine P Within group Risperidone
Total Tau (pg/ml) 731.8±430.39 728.9±414.89 0.96 755.4±460.1 749.7±568.4 0.930 0,878
Aß1-42 (pg/ml) 468.2±205.2 449.1±155.04 0.39 490.8±175.8 450.8±166.2 0,260 0,026
Phosphorylated-Tau (pg/ml) 103.2±63.38 90.8±39.63 0,147 94.9±56.20 89.1±49.92 0,147 0,210
Aß40/42 ratio (pg/ml) 0.52±0.266 0.51±0.210 0.91 0.54±0.240 0.53±0.203 0.425 0.207

Data are presented as means and standard deviations. Independent T-test was used to analyze effects between treatment groups. Depended T-test was used for analysis of within treatment group effects. Significant results considered at p<0.05