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. 2018 Oct 26;13(10):e0205950. doi: 10.1371/journal.pone.0205950

Table 2. Comparison of haemodynamic parameters according to response of VO2.

 Hemodynamic variables VO2 responders
(n = 43)
VO2 non responders
(n = 49)
p value
Respiratory minute ventilation (l min-1) 8.2 (1.3) 8 (1) 0.290
Body temperature (°C) 36.3 (1.7) 36.6 (0.4) 0.273
Capillary refill time (sec)
Pre-FC 3.6 (1.5) 3.6 (1.3) 0.908
Post-FC 3.2 (1.2) a 2.9 (1.4) a 0.289
Haemoglobin (g dl-1)
Pre-FC 11.4 (1.6) 11.2 (1.4) 0.518
Post-FC 11.2 (1.7) a 10.8 (1.4) a 0.210
HR (bpm)
Pre-FC 82 (22) 85 (19) 0.574
Post-FC 78 (21) a 81 (16) a 0.404
MAP (mmHg)
Pre-FC 74 (14) 70 (12) 0.140
Post-FC 84 (16) a 82 (12) a 0.472
SV (ml)
Pre-FC 44 (15) 42 (15) 0.652
Post-FC 60 (18) a 55 (21) a 0.263
CI (ml min-1 m-2)
Pre-FC 1.7 (0.6) 1.8 (0.7) 0.524
Post-FC 2.3 (0.7) a 2.2 (0.9) a 0.921
DO2 (ml min-1 m-2)
Pre-FC 269 (103) 274 (95) 0.811
Post-FC 339 (124) a 319 (119) a 0.428
VO2 (ml min-1 m-2)
Pre-FC 75 (34) 100 (39) 0.002
Post-FC 115 (37) a 93 (31) 0.007

Values are expressed as the mean (SD) or the median [interquartile range]. CI, indexed cardiac output; DO2, oxygen delivery; FC, fluid challenge; HR, heart rate; MAP, mean arterial pressure; SV, stroke volume; VO2, oxygen consumption

a: p<0.05 within groups (pre-/post-FC).