. 2018 Oct 26;13(10):e0205950. doi: 10.1371/journal.pone.0205950

Table 3. Comparison of perfusion parameters according to response of VO₂.

Variables	VO₂ responders (n = 43)	VO₂ non responders (n = 49)	p value
Arterial pH
Pre-FC	7.35 (0.07)	7.38 (0.2)	0.447
Post-FC	7.38 (0.05) ^a	7.39 (0.2)	0.667
Venous pH
Pre-FC	7.32 (0.05)	7.33 (0.2)	0.751
Post-FC	7.32 (0.06)	7.33 (0.2)	0.728
Oxygen arterial saturation (%)
Pre-FC	97.6 (1.2)	97.7 (1.7)	0.679
Post-FC	97.4 (1.7)	97.6 (1.4)	0.628
ScvO₂ (%)
Pre-FC	67.7 (12)	60.8 (10)	0.003
Post-FC	62.8 (9) ^a	68.4 (10) ^a	0.005
PaCO₂ (mmHg)
Pre-FC	38.4 (5)	36.4 (5)	0.068
Post-FC	37.3 (4)	36.7 (5)	0.510
PvCO₂ (mmHg)
Pre-FC	46.7 (6.1)	46.6 (5.4)	0.942
Post-FC	46.5 (5.4)	44.7 (5.3) ^a	0.104
pCO₂ gap (mmHg)
Pre-FC	8.3 (3.7)	10 (3.3)	0.020
Post-FC	9.2 (3.8)	8 (3.6) ^a	0.143
CaO₂ (ml)
Pre-FC	15.4 (2.2)	15.1 (2)	0.555
Post-FC	15 (2.2) ^a	14.4 (1.9) ^a	0.171
CvO₂ (ml)
Pre-FC	10.8 (2.7)	9.5 (2.1)	0.009
Post-FC	9.7 (2.2) ^a	10.2 (2.2) ^a	0.285
C(a-v)O₂ (ml)
Pre-FC	4.5 (1.8)	5.6 (1.6)	0.003
Post-FC	5.3 (1.2) ^a	4.2 (1.9) ^a	0.002
CaCO₂ (ml)
Pre-FC	51.2 (7)	48.3 (7.9)	0.034
Post-FC	52.1 (5.9)	49.8 (5.1) ^a	0.052
CvCO₂ (ml)
Pre-FC	57.3 (5.8)	55.6 (5.4)	0.052
Post-FC	56.9 (6.3)	53.2 (5.9) ^a	0.004
C(a-v)CO₂ content (ml)
Pre-FC	5.8 (2.9–7.4)	6.8 (4.5–7.4)	0.239
Post-FC	5.3 (3.5–7.3)	2.9 (1.6–6.1) ^a	0.023
pCO₂ gap/C(a-v)O₂ (mmHg ml^-1)
Pre-FC	1.93 (1.36–2.29)	1.89 (1.42–2.)	0.710
Post-FC	1.82 (1.39–2.21)	1.86 (1.36–2.29) ^a	0.863
C(a-v)CO₂ content /C(a-v)O₂ content ratio
Pre-FC	0.98 (0.43–2.06)	1.1 (0.86–1.85)	0.625
Post-FC	0.96 (0.59–1.39)	0.81 (0.46–1.15) ^a	0.109
Arterial lactates (mmol l^-1)
Pre-FC	1.8 (0.9)	1.9 (0.7)	0.590
Post-FC	1.8 (0.9)	2 (0.8)	0.251

Values are expressed as the mean (SD) or the median [interquartile range]. FC, fluid challenge; VO₂, oxygen consumption

^a: p<0.05 within groups (pre-/post-FC).

Table 3. Comparison of perfusion parameters according to response of VO2.

Table 3. Comparison of perfusion parameters according to response of VO₂.