Fig 1. CENP-A Mislocalization requires the H3.3 chaperones HIRA and DAXX.

A. Schematic of the definition of replicated peak sets and the calculation of ectopic CENP-A peak coverage. B. Bar chart showing the peak coverage, in kilobases, of replicated ectopic CENP-A peaks from 3 replicate ChIP-seq experiments after 72-hour knockdown of the indicated protein. C. Schematic of the intersection of peaks from control and chaperone knockdown samples. Proportional Venn diagrams showing the intersection between chaperone knockdown and control in kilobases of peak coverage. In each case, peak coverage that is newly acquired in the chaperone knockdown is in white.