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. 2018 Oct 26;13(10):e0206041. doi: 10.1371/journal.pone.0206041

Fig 5. FLIPUS affects cellular cytoskeleton.

Fig 5

A: Fold change in the mean normalized mRNA expression of genes in C2C12 cells harvested 0 h, 1 h, 2 h, 3 h, 5 h, and 7 h after 5-min-long FLIPUS stimulation compared to non-sonicated controls (OFF) of the corresponding time point. Results from three biological replicates are presented as mean ± SD. *p < 0.05 indicate changes between FLIPUS-treated and untreated cells for a selected time point. B: Exemplary F-actin stainings with Phalloidin in densely seeded non-sonicated (OFF) and FLIPUS-treated (ON) C2C12 cells. C: Exemplary F-actin stainings with Phalloidin in sparsely seeded non-sonicated (OFF) and FLIPUS-treated (ON) C2C12 cells. D: Summary of quantification results of average Phalloidin intensity normalized to cell number per image. Results from three biological replicates are presented as mean ± SD. ***p < 0.01 indicate changes between FLIPUS-treated and untreated cells.